Ketamine for depression is a fast-acting treatment option, especially for people who struggle with treatment-resistant depression (TRD)—meaning they've tried multiple antidepressants without success.
How Does it Work?
Acts on the glutamate system (instead of serotonin like most antidepressants)
Blocks NMDA receptors, which lead to a burst of brain-derived neurotrophic factor—which helps the brain form new connections and assist mood pathways reformation.
Who Does Ketamine Help?
-People with Treatment-Resistant Depression
-Those with severe suicidal ideation
-Some people with bipolar depression or PTSD (off-label)
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